DNA Structures for Cancer Therapy

Learn More about Our Research

Research Areas

DNA Structures for Cancer Therapy

Our research team creates structures from DNA and RNA as targeted medicines for the treatment of cancer. To do this, we study and control the fundamental self-assembly properties of DNA, polymers and supramolecular materials.

DNA Supramolecular Chemistry

Using only a minimal set of DNA strands, we build unique 3D structures for applications such as drug delivery and the organization of other materials. This strategy allows us to make complex constructs that will be useful for translation to clinical applications.

Expanding the DNA Toolbox

In the Sleiman lab, we work towards combining DNA with many other materials, including organic molecules, polymers, metal ions, and inorganic nanomaterials, to explore how DNA can be used to modify and organize these moieties. We make sequence-defined polymers with DNA, and study their ability to act as cancer therapies.

News

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Hanadi Sleiman awarded 2024 E. W. R. Steacie Award

McGill University Newsroom
10 January 2024

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Hanadi Sleiman elected Fellow of the Royal Society

McGill University Newsroom
10 May 2023

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McGill's Hanadi Sleiman wins 2021 Polanyi Award

McGill University Newsroom
17 November 2021

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Two McGill Researchers receive $3.3M from NSERC CREATE program funding

McGill University Newsroom
11 July 2019

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A cautionary tale for researchers working on selective drug delivery

McGill University Newsroom
10 May 2019

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Hanadi Sleiman, C.J. Li awarded Killam Research Fellowships

McGill University Newsroom
8 May 2018

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Using DNA as a printing press to create nanostructures

Chemical Institute of Canada News
May 2016

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DNA suitcases packed with gene therapy cargo

Chemistry World
21 October 2016

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From backyard pool chemical to nanomaterial

McGill University Newsroom
1 March 2016

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A ‘printing press’ for nanoparticles

McGill University Newsroom
7 January 2016

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A better way to build DNA scaffolds

McGill University Newsroom
6 May 2015

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Building tailor-made DNA nanotubes step by step

McGill University Newsroom
23 February 2015

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Complex functionality from DNA boxes and polymer snakes

JACS Article Spotlight
11 November 2014

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DNA cube programmed for an exclusive reveal

Chemistry World
15 April 2014

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DNA ‘cages’ may aid drug delivery

McGill University Newsroom
3 September 2013

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DNA motors on

Chemistry World
22 December 2011

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All aboard the DNA nanotube

Chemistry World
15 March 2010