Publications

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    2025
  1. Albumin-binding dendritic siRNA improves delivery and efficacy to solid tumors in a melanoma model
    Hassan H Fakih, Qi Tang, Ashley Summers, Katherine Y Gross, Mohamad Omar Rachid, Ken Okamura, Nuria Martinez, Hanadi F Sleiman, John E Harris, Anastasia Khvorova
    Mol. Ther. Nucleic Acids 2025, 36 (3), 102579. DOI: 10.1016/j.omtn.2025.102579
  2. Complex Donuts: Small Variations in DNA Sequence Dictate Pathway Complexity in DNA Nanotoroids
    Muhammad Ghufran Rafique, Yihao Wu, Yutong Shi, Quentin Laurent, Abdelrahman Elmanzalawy, Christopher Saab, Yu Shi, Dmytro F Perepichka, Jianing Li, Hanadi F Sleiman
    Angew. Chem. 2025, 137 (33), e202501441. DOI: 10.1002/ange.202501441
  3. Next-generation materials for nucleic acid delivery
    Roy van der Meel, Paul A Wender, Olivia M Merkel, Irene Lostalé-Seijo, Javier Montenegro, Ali Miserez, Quentin Laurent, Hanadi Sleiman, Paola Luciani
    Nat. Rev. Mater. 2025, 10, 490. DOI: 10.1038/s41578-025-00814-1
  4. UV-Cross-Linked DNA Nanomaterials Enable Robust Nanopatterning of Folate Ligands for Enhanced Cellular Uptake
    Tyler M Brown, Daniel Saliba, Jakob Hartmann, Jathavan Asohan, Chihyu Yao, Trishalina Das, Hanadi F Sleiman
    J. Am. Chem. Soc. 2025, 147 (22), 18876. DOI: 10.1021/jacs.5c02986
  5. Toward Automated DNA Nanoprinting: Advancing the Synthesis of Covalently Branched DNA
    Fangzhou Zhao, Daniel Saliba, Jathavan Asohan, Hanadi F Sleiman
    Small Methods 2025, 9 (6), 2401477. DOI: 10.1002/smtd.202401477
  6. Site‐Specific Disulfide‐Mediated Crosslinking of DNA Nanocubes for Enhanced Biological Applications
    Sinan Faiad, Quentin Laurent, Jathavan Asohan, Tyler Brown, Alexander Prinzen, Hanadi F Sleiman
    Small Sci. 2025, 5 (4), 2400471. DOI: 10.1002/smsc.202400471
  7. Self‐Assembly and Biological Properties of Highly Fluorinated Oligonucleotide Amphiphiles
    Quentin Laurent, Beatrice L Bona, Jathavan Asohan, Marta Rosati, Sinan Faiad, Francesca Baldelli Bombelli, Pierangelo Metrangolo, Hanadi F Sleiman
    Angew. Chem. 2025, 137 (7), e202419996. DOI: 10.1002/ange.202419996
  8. Photochemical Stabilization of Self‐Assembled Spherical Nucleic Acids
    Sepideh Kaviani, Haochen Bai, Trishalina Das, Jathavan Asohan, Abdelrahman Elmanzalawy, Julian Marlyn, Lea El Choueiri, Masad J Damha, Quentin Laurent, Hanadi F Sleiman
    Small 2025, 21 (7), 2407742. DOI: 10.1002/smll.202407742
  9. Sequence-defined DNA polymers: new tools for DNA nanotechnology and nucleic acid therapy
    Muhammad Ghufran Rafique, Quentin Laurent, Michael D Dore, Hassan H Fakih, Tuan Trinh, Felix J Rizzuto, Hanadi F Sleiman
    Acc. Chem. Res. 2025, 58 (2), 177. DOI: 10.1021/acs.accounts.4c00580

    10. 2024
  10. DNA Hierarchical Superstructures from Micellar Units: Stiff Hydrogels and Anisotropic Nanofibers
    Michael D Dore, Quentin Laurent, Christophe Lachance‐Brais, Trishalina Das, Xin Luo, Hanadi F Sleiman
    Chem. Eur. J. 2024, 30 (53), e202401453. DOI: 10.1002/chem.202401453
  11. Automated synthesis of DNA nanostructures
    Patricia Islas, Casey M Platnich, Yasser Gidi, Ryan Karimi, Lorianne Ginot, Daniel Saliba, Xin Luo, Gonzalo Cosa, Hanadi F Sleiman
    Adv. Mater. 2024, 36 (36), 2403477. DOI: \10.1002/adma.202403477
  12. Heat-activated growth of metastable and length-defined DNA fibers expands traditional polymer assembly
    Michael D Dore, Muhammad Ghufran Rafique, Tianxiao Peter Yang, Marlo Zorman, Casey M Platnich, Pengfei Xu, Tuan Trinh, Felix J Rizzuto, Gonzalo Cosa, Jianing Li, Alba Guarné, Hanadi F Sleiman
    Nat. Comm. 2024, 15 (1), 4384. DOI: 10.1038/s41467-024-48722-2
  13. Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo
    Samantha L Sarli, Hassan H Fakih, Karen Kelly, Gitali Devi, Julia M Rembetsy-Brown, Holly R McEachern, Chantal M Ferguson, Dimas Echeverria, Jonathan Lee, Jacquelyn Sousa, Hanadi F Sleiman, Anastasia Khvorova, Jonathan K Watts
    Nucleic Acids Res. 2024, 52 (9), 4799. DOI: 10.1093/nar/gkae260
  14. Exceptional nuclease resistance of DNA and RNA with the addition of small-molecule nucleobase mimics
    Christophe Lachance-Brais, Chihyu Yao, Alicia Reyes-Valenzuela, Jathavan Asohan, Elizabeth Guettler, Hanadi F Sleiman
    J. Am. Chem. Soc. 2024, 146 (9), 5811. DOI: 10.1021/jacs.3c07023
  15. Control Of The Assembly And Disassembly Of Spherical Nucleic Acids Is Critical For Enhanced Gene Silencing
    Jathavan Asohan, Hassan H Fakih, Trishalina Das, Hanadi F Sleiman
    ACS Nano 2024, 18, 3996-4007. DOI: 10.1021/acsnano.3c05940
  16. DNA-Mediated Peptide Assembly Into Protein Mimics
    Fangzhou Zhao, Martin Frandsen, Sabrina Capodaglio, Hanadi F Sleiman
    J. Am. Chem. Soc. 2024, 146 (3), 1946-1956. DOI: 10.1021/jacs.3c08984
  17. Automated Synthesis Of Wireframe DNA Nanotubes
    Patricia Islas, Casey M. Platnich, Yasser Gidi, Ryan Karimi, Lorianne Ginot, Gonzalo Cosa, Hanadi F Sleiman
    bioRxiv 2024, 01 (18), 576297. DOI: 10.1101/2024.01.18.576297

    18. 2023
  18. Impact Of The Core Chemistry Of Self-Assembled Spherical Nucleic Acids On Their In Vitro Fate
    Sinan Faiad, Quentin Laurent, Alexander L. Prinzen, Jathavan Asohan, Daniel Saliba, Violeta Toader, Hanadi F. Sleiman
    Angew. Chem. Int. Ed. 2023, 62 (51), e202315768. DOI: 10.1002/anie.202315768
  19. Dendritic Amphiphilic SiRNA: Selective Albumin Binding, In Vivo Efficacy And Low Toxicity
    Hassan H. Fakih, Qi Tang, Ashley Summers, Minwook Shin, Julianna E. Buchwald, Rosemary Gagnon, Vignesh N. Hariharan, Dimas Echeverria, David A. Cooper, Jonathan K. Watts, Anastasia Khvorova, Hanadi F. Sleiman
    Mol. Ther. Nucleic Acids 2023, 34 102080. DOI: 10.1016/j.omtn.2023.102080
  20. Minimalist Design Of Wireframe DNA Nanotubes: Tunable Geometry, Size, Chirality, And Dynamics
    Xin Luo, Daniel Saliba, Tianxiao Yang, Serena Gentile, Keita Mori, Patricia Islas, Trishalina Das, Neda Bagheri, Alessandro Porchetta, Alba Guarne, Gonzalo Cosa, Hanadi F. Sleiman
    Angew. Chem. Int. Ed. 2023, 62 (44), e202309869. DOI: 10.1002/anie.202309869
  21. Supramolecular Nucleic Acid-Based Organosilica Nanoparticles Responsive To Physical And Biological Inputs
    Pierre Picchetti, Stefano Volpi, Maria Sancho-Albero, Marianna Rossetti, Michael D. Dore, Tuan Trinh, Frank Biedermann, Martin Neri, Alessandro Bertucci, Alessandro Porchetta, Roberto Corradini, Hanadi F Sleiman, Luisa De Cola
    J. Am. Chem. Soc. 2023, 145 (42), 22903-22912. DOI: 10.1021/jacs.3c04345
  22. Responsive Nucleic Acid-Based Organosilica Nanoparticles
    Pierre Picchetti, Stefano Volpu, Marianna Rossetti, Michael D Dore, Tuan Trinh, Frank Biedermann, Martina Neri, Alessandro Bertucci, Alessandro Porchetta, Roberto Corradini, Hanadi Sleiman, Luisa De Cola J. Am. Chem. Soc. 2023, 145 (42), 22896-22902 DOI: 10.1021/jacs.3c00393
  23. Two-Dimensional Supramolecular Polymerization Of DNA Amphiphiles Is Driven By Sequence-Dependent DNA-Chromophore Interactions
    Muhammad Ghufran Rafique, Jacob M Remington, Finley Clark, Haochen Bai, Violeta Toader, Dmytro F Perepichka, Jianing Li, Hanadi F Sleiman
    Angew. Chem. Int. Ed. 2023, 62 (24), e202217814. DOI: 10.1002/anie.202217814
  24. Sequence-Controlled Spherical Nucleic Acids: Gene Silencing, Encapsulation, And Cellular Uptake
    Sepideh Kaviani, Hassan H Fakih, Jathavan Asohan, Adam Katolik, Masad J Damha, Hanadi F Sleiman
    Nucleic Acid Ther. 2023, 33 (4), 233-286. DOI: 10.1089/nat.2022.0062
  25. A Single Monomer Difference Can Impact The Nanostructure Output Of Precision Oligo(Phosphodiesters)
    Donatien de Rochambeau, Maciej Barłóg, Felix Rizzuto, Quentin Laurent, Xin Luo, Kai Lin Lau, Hassan S Bazzi, Hanadi F Sleiman
    Polym. Chem. 2023, 14, 3971-3977. DOI: 10.1039/D3PY00731F
  26. Small Molecule-Templated DNA Hydrogel With Record Stiffness Integrates And Releases DNA Nanostructures And Gene Silencing Nucleic Acids
    Christophe Lachance-Brais, Mostafa Rammal, Jathavan Asohan, Adam Katolik, Xin Luo, Daniel Saliba, Antranik Jonderian, Masad J. Damha, Matthew J. Harrington, Hanadi F. Sleiman
    Adv. Sci. 2023, 10 (12), 2205713. DOI: 10.1002/advs.202205713
  27. Stabilization Of Functional DNA Structures With Mild Photochemical Methods
    Tyler M. Brown, Hassan H. Fakih, Daniel Saliba, Jathavan Asohan, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2023, 145 (4), 2142–2151 DOI: 10.1021/jacs.2c08808
  28. Programming Rigidity Into Size-Defined Wireframe DNA Nanotubes
    Daniel Saliba, Xin Luo, Felix Rizzuto, Hanadi Sleiman
    Nanoscale 2023, 15, 5403-5413. DOI: 10.1039/D2NR06185F

    29. 2022
  29. DNA Sequence And Length Dictate The Assembly Of Nucleic Acid Block Copolymers
    Felix J. Rizzuto, Michael D. Dore, Muhammad Ghufran Rafique, Xin Luo, and Hanadi F. Sleiman
    J. Am. Chem. Soc. 2022, 144 (27), 12272–12279 DOI: 10.1021/jacs.2c03506
  30. Using Transient Equilibria (TREQ) To Measure The Thermodynamics Of Slowly Assembling Supramolecular Systems
    Christopher Hennecker, Christophe Lachance-Brais, Hanadi F. Sleiman and Anthony Mittermaier
    Sci. Adv. 2022, 8 (14), eabm8455. DOI: 10.1126/sciadv.abm8455
  31. Asymmetric Patterning Drives The Folding Of A Tripodal DNA Nanotweezer
    Daniel Saliba, Tuan Trinh, Christophe Lachance-Brais, Alexander L. Prinzen, Felix J. Rizzuto, Donatien de Rochambeau and Hanadi F. Sleiman
    Chem. Sci. 2022, 13, 74-80. DOI: 10.1039/D1SC04793K

    32. 2021
  32. Tuning DNA Supramolecular Polymers By The Addition Of Small, Functionalized Nucleobase Mimics
    Christophe Lachance-Brais, Christopher D. Hennecker, Asem Alenaizan, Xin Luo, Violeta Toader, Monica Taing, C. David Sherrill, Anthony K. Mittermaier, and Hanadi F. Sleiman*
    J. Am. Chem. Soc. 2021, 143 (47), 19824-19833. DOI: 10.1021/jacs.1c08972
  33. Thermosetting Supramolecular Polymerization Of Compartmentalized DNA Fibers With Stereo Sequence And Length Control
    Michael D. Dore, Tuan Trinh, Marlo Zorman, Donatien de Rochambeau, Casey M. Platnich, Pengfei Xu, Xin Luo, Jacob M. Remington, Violeta Toader, Gonzalo Cosa, Jianing Li, Hanadi F. Sleiman
    Chem 2021, 7 (9), 2395-2414. DOI: 10.1016/j.chempr.2021.05.022
  34. DNA Nanostructures: Current Challenges And Opportunities For Cellular Delivery
    Aurélie Lacroix and Hanadi F. Sleiman*
    ACS Nano 2021, 15 (3), 3631-3645. DOI: 10.1021/acsnano.0c06136
  35. A Dissipative Pathway For The Structural Evolution Of DNA Fibres
    Felix J. Rizzuto, Casey M. Platnich, Xin Luo, Yao Shen, Michael D. Dore, Christophe Lachance-Brais, Alba Guarné, Gonzalo Cosa & Hanadi F. Sleiman
    Nat. Chem. 2021, 13 843-849. DOI: 10.1038/s41557-021-00751-w
  36. Design And Enhanced Gene Silencing Activity Of Spherical 2′-Fluoroarabinose Nucleic Acids (FANA-SNAs)
    Hassan H Fakih, Adam Katolik, Elise Malek-Adamian, Johans J Fakhoury, Sepideh Kaviani, Masad J Damha, Hanadi F Sleiman
    Chem. Sci. 2021, 12, 2993-3003. 10.1039/D0SC06645A

    37. 2020
  37. A Poly(Thymine)–Melamine Duplex For The Assembly Of DNA Nanomaterials
    Qian Li, Jiemin Zhao, Longfei Liu, Sagun Jonchhe, Felix J Rizzuto, Shankar Mandal, Huawei He, Sansen Wei, Hanadi F Sleiman, Hanbin Mao, Chengde Mao
    Nat. Mater. 2020, 19 (9), 1012-1018. DOI: 10.1038/s41563-020-0728-2
  38. Molecular Printing With DNA Nanotechnology
    Felix J. Rizzuto, Tuan Trinh, Hanadi F. Sleiman
    Chem 2020, 6 (7), 1560-1574. DOI: 10.1016/j.chempr.2020.06.012
  39. Single-Molecule Methods In Structural DNA Nanotechnology
    Casey M. Platnich, Felix J. Rizzuto, Gonzalo Cosa, Hanadi F. Sleiman
    Chem. Soc. Rev. 2020, 49, 4220-4233. DOI: 10.1039/C9CS00776H
  40. Amplified Self‐Immolative Release Of Small Molecules By Spatial Isolation Of Reactive Groups On DNA‐Minimal Architectures
    Alexander L Prinzen, Daniel Saliba, Christopher Hennecker, Tuan Trinh, Anthony Mittermaier, Hanadi F Sleiman
    Angew. Chem. Int. Ed. 2020, 59 (31), 12900-12908. DOI: 10.1002/anie.202001123
  41. Selection Of A Metal Ligand Modified DNAzyme For Detecting Ni2+
    Wei Ren, Po-Jung Jimmy Huang, Donatien de Rochambeau, Woohyun J Moon, Jinyi Zhang, Mingsheng Lyu, Shujun Wang, Hanadi Sleiman, Juewen Liu
    Biosens. Bioelectron. 2020, 165 112285. DOI: 10.1016/j.bios.2020.112285
  42. Detailed Cellular Assessment Of Albumin-Bound Oligonucleotides: Increased Stability And Lower Non-Specific Cell Uptake
    Aurélie Lacroix, Hassan H Fakih, Hanadi F Sleiman
    J. Controlled Release 2020, 324, 34-46. DOI: 10.1016/j.jconrel.2020.04.020
  43. Target Self‐Enhanced Selectivity In Metal‐Specific DNAzymes
    Po‐Jung Jimmy Huang, Donatien de Rochambeau, Hanadi F Sleiman, Juewen Liu
    Angew. Chem. Int. Ed., 2020, 59 (9), 3573-3577. DOI: 10.1002/anie.201915675
  44. The Assemble, Grow And Lift-Off (AGLO) Strategy To Construct Complex Gold Nanostructures With Pre-Designed Morphologies
    Xin Luo, Christophe Lachance-Brais, Amy Bantle, Hanadi F Sleiman
    Chem. Sci. 2020, 19, 4911-4921. DOI: 10.1039/D0SC00553C
  45. Sequence-Defined DNA Amphiphiles For Drug Delivery: Synthesis And Self-Assembly
    Michael D Dore, Hanadi F Sleiman
    In Nucleic Acid Detection and Structural Investigations, Astakhova, K.; Bukhari, S. (eds.) Methods Mol. Biol. 2020, 2063, 87-100. DOI: 10.1007/978-1-0716-0138-9_8
  46. Transition Metal‐Functionalized DNA Double‐Crossover Tiles: Enhanced Stability And Chirality Transfer To Metal Centers
    Alexander Rousina-Webb, Christophe Lachance-Brais, Felix J. Rizzuto, Mohammed Askari, Hanadi F. Sleiman
    Angew. Chem. Int. Ed., 2020, 59 (10), 4091-4098. DOI: 10.1002/anie.201913956

    47. 2019
  47. Advancing Wireframe DNA Nanostructures Using Single-Molecule Fluorescence Microscopy Techniques
    Casey M. Platnich, Amani A. Hariri, Hanadi F. Sleiman, Gonzalo Cosa
    Acc. Chem. Res. 2019, 52 (11), 3199-3210. DOI: 10.1021/acs.accounts.9b00424
  48. Bottom‐Up Characterization And Self‐Assembly Of Electrogenerated Chemiluminescence Active Ruthenium Nanospheres
    Andrew S. Danis, Kimberly L. Metera, Nicholas A. Payne, Hanadi F. Sleiman, Janine Mauzeroll
    ChemElectroChem 2019, 6 (13), 3499-3506. DOI: 10.1002/celc.201900702
  49. Charting A Course For Chemistry
    Hanadi F. Sleiman, et. al.
    Nat. Chem. 2019, 11, 286-294. DOI: 10.1038/s41557-019-0236-7
  50. Spatial Presentation Of Cholesterol Units On A DNA Cube As A Determinant Of Membrane Protein-Mimicking Functions
    Pongphak Chidchob, Daniel Offenbartl-Stiegert, Dillon McCarthy, Xin Luo, Jianing Li, Stefan Howorka, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2019, 141 (2), 1100-1108. DOI: 10.1021/jacs.8b11898
  51. Remote control Of charge transport and chiral induction along a DNA-metallohelicate
    Mohammad S. Askari, Christophe Lachance-Brais, Felix J. Rizzuto, Violeta Toader, Hanadi Sleiman
    Nanoscale 2019, 11, 11879-11884. 10.1039/C9NR03212F
  52. Uptake and fate of fluorescently labeled DNA nanostructures in cellular environments: a cautionary tale
    Aurélie Lacroix, Empar Vengut-Climent, Donatien de Rochambeau, Hanadi F. Sleiman
    ACS Cent. Sci. 2019, 5 (5), 882-891. 10.1021/acscentsci.9b00174
  53. Minimalist Design Of A Stimuli-Responsive Spherical Nucleic Acid For Conditional Delivery Of Oligonucleotide Therapeutics
    Hassan H. Fakih, Johans J. Fakhoury, Danny Bousmail, Hanadi F. Sleiman
    ACS Appl. Mater. Interfaces 2019, 11 (15), 13912-13920. DOI: 10.1021/acsami.8b18790
  54. “Printing” DNA Strand Patterns On Small Molecules With Control Of Valency, Directionality, And Sequence
    Tuan Trinh, Daniel Saliba, Chenyi Liao, Donatien de Rochambeau, Alexander Lee Prinzen, Jianing Li, Hanadi F. Sleiman
    Angew. Chem. Int. Ed., 2019, 58 (10), 3042–3047. DOI: 10.1002/anie.201809251
  55. Design Strategy To Access SiRNA-Encapsulating DNA “Nanosuitcases” That Can Conditionally Release Their Cargo
    Katherine E. Bujold, Hassan H. Fakih, Hanadi F. Sleiman
    In RNA Interference and Cancer Therapy. Dinesh Kumar, L. (eds.) Methods Mol. Biol., RNA Interference and Cancer Therapy, p. 69-81. DOI: 10.1007/978-1-4939-9220-1_6

    56. 2018
  56. Kinetics Of Strand Displacement And Hybridization On Wireframe DNA Nanostructures: Dissecting The Roles Of Size, Morphology, And Rigidity
    Casey M. Platnich, Amani A. Hariri, Janane F. Rahbani, Jesse B. Gordon, Hanadi F. Sleiman, Gonzalo Cosa
    ACS Nano 2018, 12 (12), 12836-12846. DOI: 10.1021/acsnano.8b08016
  57. Templated Synthesis Of Spherical RNA Nanoparticles With Gene Silencing Activity
    Michael D. Dore, Johans J. Fakhoury, Aurélie Lacroix, Hanadi F. Sleiman
    Chem. Commun. 2018, 54, 11296-11299. DOI: 10.1039/C8CC06994H
  58. Modular Strategy To Expand The Chemical Diversity Of DNA And Sequence-Controlled Polymers
    Donatien de Rochambeau, Yuanye Sun, Maciej Barlog, Hassan S. Bazzi, Hanadi F. Sleiman
    J. Org. Chem. 2018, 83 (17), 9774-9786. DOI: 10.1021/acs.joc.8b01184
  59. DNA-Imprinted Polymer Nanoparticles With Monodispersity And Prescribed DNA-Strand Patterns
    Tuan Trinh, Chenyi Liao, Violeta Toader, Maciej Barłóg, Hassan S. Bazzi, Jianing Li, Hanadi F. Sleiman
    Nat. Chem. 2018, 10, 184-192. DOI: 10.1038/nchem.2893
  60. Mapping The Energy Landscapes Of Supramolecular Assembly By Thermal Hysteresis
    Robert W. Harkness V, Nicole Avakyan, Hanadi F. Sleiman, Anthony K. Mittermaier
    Nat. Commun. 2018, 9, 3152. DOI: 10.1038/s41467-018-05502-z
  61. DNA Nanostructures At The Interface With Biology
    Katherine Bujold, Aurelie Lacroix, Hanadi Sleiman
    Chem 2018, 43, 495-521. DOI: 10.1016/j.chempr.2018.02.005
  62. Cyanine-Mediated DNA Nanofiber Growth With Controlled Dimensionality
    Danny Bousmail, Pongphak Chidchob, Hanadi Sleiman
    J. Am. Chem. Soc. 2018, 140 30, 9518–9530. DOI: 10.1021/jacs.8b04157
  63. Recent Advances In DNA Nanotechnology
    Pongphak Chidchob, Hanadi Sleiman
    Curr. Opin. Chem. Biol. 2018, 46, 63-70. DOI: 10.1016/j.cbpa.2018.04.012
  64. Encapsulation Of Gold Nanoparticles Into DNA Minimal Nanocages For Complex Anisotropic Functionalization And Assembly
    Xin Luo, Hanadi F. Sleiman
    Small 2018, 14 5, 1702660. DOI: 10.1002/smll.201702660
  65. Single-Stranded Templates As Railroad Tracks For Hierarchical Assembly Of DNA Origami
    Janane Rahbani, John Hsu, Pongphak Chidchob, Hanadi F. Sleiman
    Nanoscale 2018, 10 (29), 13994-13999. DOI: 10.1039/C8NR03185A

    66. 2017
  66. DNA Nanotechnology
    Nadrian C. Seeman, Hanadi F. Sleiman
    Nat. Rev. Mater. 2017, 3 17068. DOI: 10.1038/natrevmats.2017.68
  67. Efficient And Rapid Mechanochemical Assembly Of Platinum(II) Squares For Guanine Quadruplex Targeting
    Amine Garci, Katherine J. Castor, Johans Fakhoury, Jean-Louis Do, Justin Di Trani, Pongphak Chidchob, Robin S. Stein, Anthony K. Mittermaier, Tomislav Friščić, Hanadi Sleiman
    J. Am. Chem. Soc. 2017, 139 (46), 16913-16922. DOI: 10.1021/jacs.7b09819
  68. Long-Range Ordering Of Blunt-Ended DNA Tiles On Supported Lipid Bilayers
    Nicole Avakyan, Justin W. Conway, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2017, 139 (34), 12027-12034. DOI: 10.1021/jacs.7b06572
  69. Stoichiometry And Dispersity Of DNA Nanostructures Using Photobleaching Pair Correlation Analysis
    Amani A. Hariri, Graham D. Hamblin, Jack S. Hardwick, Robert Godin, Jean-Francois Desjardins, Paul W. Wiseman, Hanadi F. Sleiman, Gonzalo Cosa
    Bioconjugate Chem. 2017, 28 (9), 2340-2349. DOI: 10.1021/acs.bioconjchem.7b00369
  70. Precision Spherical Nucleic Acids For Delivery Of Anticancer Drugs
    Danny Bousmail, Lilian Amrein, Johans J. Fakhoury, Hassan H. Fakih, John C. C. Hsu, Lawrence Panasc, Hanadi F. Sleiman
    Chem. Sci. 2017, 8 (9), 6218-6229. DOI: 10.1039/C7SC01619K
  71. Development Of DNA Nanostructures For High Affinity Binding To Human Serum Albumin
    Aurélie Lacroix, Thomas G. W. Edwardson, Mark A. Hancock, Michael D. Dore, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2017, 139 (21), 7355-7362. DOI: 10.1021/jacs.7b02917
  72. Supramolecular DNA Nanotechnology
    Justin Conway, Hanadi F. Sleiman
    In Comprehensive Supramolecular Chemistry II. Elsevier, 2017. p441-486. DOI: 10.1016/B978-0-12-409547-2.12548-X
  73. Cuvette‐Based Electrogenerated Chemiluminescence Detection System For The Assessment Of Polymerizable Ruthenium Luminophores
    Andrew S. Danis, William L. Odette, Samuel C. Perry, Sylvain Canesi, Hanadi F. Sleiman, Janine Mauzeroll
    ChemElectroChem 2017, 4 (7), 1736–1743. DOI: 10.1002/celc.201600879

    74. 2016
  74. Optimized DNA “Nanosuitcases” For Encapsulation And Conditional Release Of siRNA
    Katherine E. Bujold, John C. C. Hsu, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2016, 138 (42) 14030–14038. DOI: 10.1021/jacs.6b08369
  75. DNA Micelles As Nanoreactors: Efficient DNA Functionalization With Hydrophobic Organic Molecules
    Tuan Trinh, Pongphak Chidchob, Hassan S. Bazzi, Hanadi F. Sleiman
    Chem. Commun. 2016, 52, 10914-10917. DOI: 10.1039/C6CC04970B
  76. Minimalist Approach To Complexity: Templating The Assembly Of DNA Tile Structures With Sequentially Grown Input Strands
    Kai Lin Lau, Hanadi Sleiman
    ACS Nano 2016, 10 (7), 6542–6551. DOI: 10.1021/acsnano.6b00134
  77. “DNA–Teflon” Sequence-Controlled Polymers
    Donatien de Rochambeau, Maciej Barłóg, Thomas Edwardson, Johans Fakhoury, Robin Stein, Hassan Bazzi, Hanadi Sleiman
    Polym. Chem. 2016, 7 (31), 4998-5003. DOI: 10.1039/C6PY00532B
  78. Synergy Of Two Assembly Languages In DNA Nanostructures: Self-Assembly Of Sequence-Defined Polymers On DNA Cages
    Pongphak Chidchob, Thomas G. W. Edwardson, Christopher J. Serpell, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2016, 138 (13), 4416–4425. DOI: 10.1021/jacs.5b12953
  79. Reprogramming The Assembly Of Unmodified DNA With A Small Molecule
    Nicole Avakyan, Andrea Greschner, Faisal Aldaye, Violeta Toader, Anne Petitjean, Hanadi Sleiman
    Nature Chem. 2016, 8, 368-376. DOI: 10.1038/nchem.2451
  80. Transfer Of Molecular Recognition Information From DNA Nanostructures To Gold Nanoparticles
    Thomas G. W. Edwardson, Kai Lin Lau, Danny Bousmail, Hanadi Sleiman
    Nature Chem. 2016, 8, 162–170. DOI: 10.1038/nchem.2420

    81. 2015
  81. Dynamic DNA Nanotubes: Reversible Switching between Single and Double-Stranded Forms, and Effect of Base Deletions
    Janane Rahbani, Amani Hariri, Gonzalo Cosa, Hanadi Sleiman
    ACS Nano 2015, 9 (12), 11898–11908. DOI: 10.1021/acsnano.5b04387
  82. Antisense Precision Polymer Micelles Require Less Poly(Ethylenimine) For Efficient Gene Knockdown
    Johans Fakhoury, Tom Edwardson, Justin Conway, Tuan Trinh, Farhad Khan, Maciej Barlog, Hassan Bazzi, Hanadi Sleiman
    Nanoscale 2015, 7 (48), 20625-20634. DOI: 10.1039/C5NR05157F
  83. Cyclometalated Iridium(III) Imidazole Phenanthroline Complexes as Luminescent and Electrochemiluminescent G-Quadruplex DNA Binders
    Katherine J. Castor, Kimberly L. Metera, Ushula M. Tefashe, Christopher J. Serpell, Janine Mauzeroll, Hanadi F. Sleiman
    Inorg. Chem. 2015, 54 (14), 6958–6967. DOI: 10.1021/acs.inorgchem.5b00921
  84. Sequential Growth of Long DNA Strands with User-Defined Patterns for Nanostructures and Scaffolds
    Graham D. Hamblin, Janane F. Rahbani, Hanadi F. Sleiman
    Nat. Commun. 2015, 6 7065. DOI: 10.1038/ncomms8065
  85. Stepwise Growth Of Surface-Grafted DNA Nanotubes Visualized at the Single Molecule Level
    Amani A. Hariri, Graham D. Hamblin, Yasser Gidi, Hanadi F. Sleiman, Gonzalo Cosa
    Nature Chem. 2015, 7, 295-300. DOI: 10.1038/nchem.2184
  86. Modulation of Charge Transport Across Double-Stranded DNA by the Site-Specific Incorporation of Copper Bis-Phenanthroline Complexes
    Philippe Dauphin-Ducharme, Fiora Rosati, Andrea Greschner, A. Dowine De Bruijn, Danielle Salvatore, Violeta Toader, Kai Lin Lau, Janine Mauzeroll, Hanadi Sleiman
    Langmuir 2015, 31 (5), 1850–1854. DOI: 10.1021/la504300g

    87. 2014
  87. Precision Polymers And 3D DNA Nanostructures: Emergent Assemblies From New Parameter Space
    Christopher J. Serpell, Thomas G. W. Edwardson, Pongphak Chidchob, Karina M. M. Carneiro, Hanadi F. Sleiman
    J. Am. Chem. Soc. 2014, 136 (44), 15767–15774. DOI: 10.1021/ja509192n
  88. Sequence-Responsive Unzipping DNA Cubes With Tunable Cellular Uptake Profiles
    Katherine E. Bujold, Johans Fakhoury, Thomas G. W. Edwardson, Karina M. M. Carneiro, Joel Neves Briard, Antoine G. Godin, Lilian Amrein, Graham D. Hamblin, Lawrence C. Panasci, Paul W. Wiseman, Hanadi F. Sleiman
    Chem. Sci. 2014, 5 (6), 2449-2455. DOI: 10.1039/C4SC00646A
  89. Dynamic Behavior of DNA Cages Anchored on Spherically Supported Lipid Bilayers
    J. W. Conway, C. Madwar, T. G. Edwardson, C. K. McLaughlin, J. Fahkoury, R. B. Lennox, H. F. Sleiman
    J. Am. Chem. Soc. 2014, 136 (37), 12987-12997. DOI: 10.1021/ja506095n
  90. Controlled Growth of DNA Structures from Repeating Units Using the Vernier Mechanism
    Andrea A. Greschner, Katherine. E. Bujold, Hanadi F. Sleiman
    Biomacromolecules 2014, 15 (8), 3002-3008. DOI: 10.1021/bm500613s
  91. Mechatronic DNA Devices Driven by a G-Quadruplex-Binding Platinum Ligand
    Yu Chuan Huang, Katherine J. Castor, Hanadi F. Sleiman, Dipankar Sena
    Bioorg. Med. Chem. 2014, 22 (16), 4376-4383. DOI: 10.1016/j.bmc.2014.05.023
  92. An Efficient and Modular Route to Sequence-Defined Polymers Appended to DNA
    Thomas G. W. Edwardson, Karina M. M. Carneiro, Christopher J. Serpell, Hanadi F. Sleiman
    Angew. Chem. Int. Ed., 2014, 53 (18), 4567-4571. DOI: 10.1002/anie.201310937
  93. Development and Characterization of Gene Silencing DNA Cages
    Johans J. Fakhoury, Christopher K. McLaughlin, Thomas W. Edwardson, Justin W. Conway, Hanadi F. Sleiman
    Biomacromolecules 2014, 15 (1), 276-282. DOI: 10.1021/bm401532n
  94. Gold Nanoparticle 3D-DNA Building Blocks: High Purity Preparation and Use for Modular Access to Nanoparticle Assemblies
    Kai Lin Lau, Graham D. Hamblin, Hanadi F. Sleiman
    Small 2014, 10 (4), 660-666. DOI: 10.1002/smll.201301562

    95. 2013
  95. A platinum(II) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-Kit G-quadruplex motif
    Castor KJ, Liu Z, Fakhoury J, Hancock MA, Mittermaier A, Moitessier N, Sleiman HF
    Chem. Eur. J. 2013, Dec 23;19(52):17836-45. DOI: 10.1002/chem.201301590
  96. Site-specific positioning of dendritic alkyl chains on DNA cages enables their geometry-dependent self-assembly
    Edwardson TG, Carneiro KM, McLaughlin CK, Serpell CJ, Sleiman HF
    Nat. Chem. 2013, Oct;5(10):868-75. DOI: 10.1038/nchem.1745
  97. Electrogenerated chemiluminescence of iridium-containing ROMP block copolymer and self-assembled micelles
    Tefashe UM, Metera KL, Sleiman HF, Mauzeroll J
    Langmuir 2013, Oct 15; 29(41):12866-73. DOI: 10.1021/la402518v
  98. Intercalators as molecular chaperones in DNA self-assembly
    Greschner AA, Bujold KE, Sleiman HF
    J. Am. Chem. Soc. 2013, Jul 31;135(30):11283-8. DOI: 10.1021/ja404402b
  99. Long-range assembly of DNA into nanofibers and highly ordered networks
    Carneiro KM, Avakyan N, Sleiman HF
    WIREs Nanomed. Nanobiotechnol. 2013, 5 (3), 266-285. DOI: 10.1002/wnan.1218
  100. Simple design for DNA nanotubes from a minimal set of unmodified strands: rapid, room-temperature assembly and readily tunable structure
    Hamblin GD, Hariri AA, Carneiro KM, Lau KL, Cosa G, Sleiman HF
    ACS Nano 2013, 7 (4), 3022-3028. DOI: 10.1021/nn4006329

    101. 2012
  101. The role of organic linkers in directing DNA self-assembly and significantly stabilizing DNA duplexes
    Greschner AA, Toader V, Sleiman HF
    J. Am. Chem. Soc. 2012, 134 (35), 14382-14389. DOI: 10.1021/ja3033197
  102. Three-dimensional organization of block copolymers on “DNA-minimal” scaffolds
    McLaughlin CK, Hamblin GD, Hänni KD, Conway JW, Nayak MK, Carneiro KM, Bazzi HS, Sleiman HF
    J. Am. Chem. Soc. 2012 134 (9), 4280-4286. DOI: 10.1021/ja210313p
  103. Rolling circle amplification-templated DNA nanotubes show increased stability and cell penetration ability
    Hamblin GD, Carneiro KM, Fakhoury JF, Bujold KE, Sleiman HF
    J. Am. Chem. Soc. 2012, 134 (6), 2888-2891. Erratum in: J. Am. Chem. Soc. 2012, 134 (11), 5426. DOI: 10.1021/ja2107492, 10.1021/ja301573b
  104. Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes
    Castor KJ, Mancini J, Fakhoury J, Weill N, Kieltyka R, Englebienne P, Avakyan N, Mittermaier A, Autexier C, Moitessier N, Sleiman HF
    ChemMedChem 2012, 7 (1), 85-94. DOI: 10.1002/cmdc.201100453

    105. 2011
  105. Supramolecular DNA assembly
    McLaughlin CK, Hamblin GD, Sleiman HF.
    Chem. Soc. Rev. 2011 40 (12), 5647-5656. DOI: 10.1039/C1CS15253J
  106. A facile, modular and high yield method to assemble three-dimensional DNA structures
    McLaughlin CK, Hamblin GD, Aldaye FA, Yang H, Sleiman HF
    Chem. Commun. 2011, 47 (31), 8925-8927. DOI: 10.1039/C1CC11726B
  107. Self-assembly of metal-DNA triangles and DNA nanotubes with synthetic junctions
    Yang H, Lo PK, McLaughlin CK, Hamblin GD, Aldaye FA, Sleiman HF
    In DNA Nanotechnology. Eds: Zuccheri, G.; Samori, B. Methods Mol. Biol. 2011, 749, 33-47. DOI: 10.1007/978-1-61779-142-0_3
  108. Chiral metal-DNA four-arm junctions and metalated nanotubular structures
    Yang H, Altvater F, de Bruijn AD, McLaughlin CK, Lo PK, Sleiman HF
    Angew. Chem. Int. Ed. 2011, 50 (20), 4620-4263. DOI: 10.1002/anie.201007403

    109. 2010 and earlier
  109. Loading and selective release of cargo in DNA nanotubes with longitudinal variation
    Lo PK, Karam P, Aldaye FA, McLaughlin CK, Hamblin GD, Cosa G, Sleiman HF
    Nat. Chem. 2010 Apr;2(4):319-28. DOI: 10.1038/nchem.575
  110. Self-assembly of three-dimensional DNA nanostructures and potential biological applications
    Lo PK, Metera KL, Sleiman HF
    Curr. Opin. Chem. Biol. 2010, 14 (5), 597-607. DOI: 10.1016/j.cbpa.2010.08.002
  111. Stable gold nanoparticle conjugation to internal DNA positions: facile generation of discrete gold nanoparticle-DNA assemblies
    Wen Y, McLaughlin CK, Lo PK, Yang H, Sleiman HF
    Bioconjugate Chem. 2010, 21 (8), 1413-1416. DOI: 10.1021/bc100160k
  112. Templated synthesis of DNA nanotubes with controlled, predetermined lengths
    Lo PK, Altvater F, Sleiman HF
    J. Am. Chem. Soc. 2010, 132 (30), 10212-10214. DOI: 10.1021/ja1017442
  113. Long-range assembly of DNA into nanofibers and highly ordered networks using a block copolymer approach
    Carneiro KM, Aldaye FA, Sleiman HF
    J. Am. Chem. Soc. 2010, 132 (2), 679-685. DOI: 10.1021/ja907735m
  114. Templated ligand environments for the selective incorporation of different metals into DNA
    Yang H, Rys AZ, McLaughlin CK, Sleiman HF
    Angew. Chem. Int. Ed. 2009, 48 (52), 9919-9923. DOI: 10.1002/anie.200904186
  115. Metal-nucleic acid cages
    Yang H, McLaughlin CK, Aldaye FA, Hamblin GD, Rys AZ, Rouiller I, Sleiman HF
    Nat. Chem. 2009 1 (5), 390-396. DOI: 10.1038/nchem.290
  116. Modular construction of DNA nanotubes of tunable geometry and single- or double-stranded character
    Aldaye FA, Lo PK, Karam P, McLaughlin CK, Cosa G, Sleiman HF
    Nat. Nanotechnol. 2009 4 (6), 349-52. DOI: 10.1038/nnano.2009.72
  117. Nucleobase-templated polymerization: copying the chain length and polydispersity of living polymers into conjugated polymers
    Lo PK, Sleiman HF.
    J. Am. Chem. Soc. 2009, 131 (12), 4182-4183. DOI: 10.1021/ja809613n
  118. Evaluation of binding selectivities and affinities of platinum-based quadruplex interactive complexes by electrospray ionization mass spectrometry
    Pierce SE, Kieltyka R, Sleiman HF, Brodbelt JS
    Biopolymers 2009, 91 (4), 233-243. doi: 10.1002/bip.21130. DOI: 10.1002/bip.21130
  119. Assembling materials with DNA as the guide
    Aldaye FA, Palmer AL, Sleiman HF
    Science 2008, 321 (5897), 1795-1799. DOI: 10.1126/science.1154533
  120. A platinum supramolecular square as an effective G-quadruplex binder and telomerase inhibitor
    Kieltyka R, Englebienne P, Fakhoury J, Autexier C, Moitessier N, Sleiman HF
    J. Am. Chem. Soc. 2008, 130 (31), 10040-10041. DOI: 10.1021/ja8014023
  121. Templated synthesis of highly stable, electroactive, and dynamic metal-DNA branched junctions
    Yang H, Sleiman HF
    Angew. Chem. Int. Ed. 2008, 47 (13), 2443-2446. DOI: 10.1002/anie.200703741
  122. Platinum phenanthroimidazole complexes as G-quadruplex DNA selective binders
    Kieltyka R, Fakhoury J, Moitessier N, Sleiman HF
    Chem. Eur. J. 2008, 14 (4), 1145-1154. DOI: 10.1002/chem.200700783
  123. Modular access to structurally switchable 3D discrete DNA assemblies
    Aldaye FA, Sleiman HF
    J. Am. Chem. Soc. 2007, 129 (44), 13376-13377. DOI: 10.1021/ja075966q
  124. Guest-mediated access to a single DNA nanostructure from a library of multiple assemblies
    Aldaye FA, Sleiman HF
    J. Am. Chem. Soc. 2007, 129 (33), 10070-10071. DOI: 10.1021/ja073305n
  125. DNA-protein noncovalent cross-linking: ruthenium dipyridophenazine biotin complex for the assembly of proteins and gold nanoparticles on DNA templates
    Slim M, Durisic N, Grutter P, Sleiman HF
    ChemBioChem 2007, 8 (7), 804-812. DOI: 10.1002/cbic.200600550
  126. Dynamic DNA templates for discrete gold nanoparticle assemblies: control of geometry, modularity, write/erase and structural switching
    Aldaye FA, Sleiman HF
    J. Am. Chem. Soc. 2007, 129 (14), 4130-4131. DOI: 10.1021/ja070017i
  127. Molecule-responsive block copolymer micelles
    Ishihara Y, Bazzi HS, Toader V, Godin F, Sleiman HF
    Chem. Eur. J. 2007, 13 (16), 4560-4570. DOI: 10.1002/chem.200601423
  128. Sequential self-assembly of a DNA hexagon as a template for the organization of gold nanoparticles
    Aldaye FA, Sleiman HF
    Angew. Chem. Int. Ed. 2006, 45 (14), 2204-2209. DOI: 10.1002/anie.200502481
  129. Hydrogen-bond self-assembly of DNA-analogues into hexameric rosettes
    Rakotondradany F, Palmer A, Toader V, Chen B, Whitehead MA, Sleiman HF
    Chem. Commun. 2005, 5441-5443. Epub 2005 Oct 4. DOI: 10.1039/B511984G
  130. Self-assembly of cyclic metal-DNA nanostructures using ruthenium tris(bipyridine)-branched oligonucleotides
    Mitra, D.; Di Cesare, N.; Sleiman, H.F.
    Angew. Chem. Int. Ed. 2004, 43 (43), 5804-5808. DOI: 10.1002/anie.200460255
  131. Ruthenium(II)-phenanthroline-biotin complexes: synthesis and luminescence enhancement upon binding to avidin
    Slim, M.; Sleiman H.F.
    Bioconjugate Chem. 2004, 15 (5), 949-953. DOI: 10.1021/bc049919o
  132. Ruthenium(II) dipyridoquinoxaline-norbornene: synthesis, properties, crystal structure, and use as a ROMP monomer
    Rezvani A, Bazzi HS, Chen B, Rakotondradany F, Sleiman HF
    i>Inorg. Chem. 2004 43 (16), 5112-5119. DOI: 10.1021/ic0498438
  133. Photoresponsive supramolecular systems: self-assembly of azodibenzoic acid linear tapes and cyclic tetramers
    Rakotondradany F, Whitehead MA, Lebuis AM, Sleiman HF.
    Chem. Eur. J. 2003, 9 (19), 4771-4780. DOI: 10.1002/chem.200304864
  134. Solid-Phase Synthesis of Transition Metal Linked, Branched Oligonucleotides
    Vargas-Baca, I.; Mitra, D.; Zulyniak, H. J.; Banerjee, J., Sleiman, H.F.
    Angew. Chem. Int. Ed. 2001, 40 (24), 4629-4632. DOI: 10.1002/1521-3773(20011217)40:24<4629::AID-ANIE4629>3.0.CO;2-S

Patent Applications
  1. Tumor delivery of dendritic oligonucleotides
    Hassan H Fakih, Hanadi Sleiman, Anastasia Khvorova, John E Harris, Qi Tang, Ken Okamura
    US Patent Application 18/609,299
  2. Dendritic conjugates for the lung delivery of therapeutic oligonucleotides
    Hassan H Fakih, Hanadi Sleiman, Anastasia Khvorova, Jonathan K Watts, Qi Tang, Minwook Shin
    US Patent Application 18/592,676
  3. Dendritic conjugates for the brain delivery of therapeutic oligonucleotides
    Hassan H Fakih, Hanadi Sleiman, Anastasia Khvorova, Jonathan K Watts, Samantha Sarli
    US Patent Application 18/609,621
  4. Dendritic conjugates for the skin delivery of therapeutic oligonucleotides
    Hassan H Fakih, Hanadi Sleiman, Anastasia Khvorova, Qi Tang, Katherine Gross, John E Harris, Julia Alterman, Mohammad Zain Ul Abideen, Raymond Furgal
    US Patent Application 18/592,943
  5. Topical delivery of therapeutic oligonucleotides
    Hassan H Fakih, Hanadi Sleiman, Anastasia Khvorova, Qi Tang, John E Harris, Julia Alterman, Mohammad Zain Ul Abideen, Raymond Furgal
    US Patent Application 18/593,212
  6. Ultrabright DNA Nanostructures For Biosensing
    Xighua Shi, Haidong Huang, Hassan H Fakih, Hanadi F Sleiman
    US Patent Application 18/048,006
  7. DNA-Encoded Functionalized Aptamers
    Hanadi F Sleiman, Donatien De Rochambeau, Maureen McKeague, Serhii Hirka, Daniel Saliba, Shaun Ian Anderson
    US Patent Application 18/001,023
  8. Reagents based on a tertiary amine backbone to introduce chemical functionality in nucleic acids and sequence-controlled polymers
    Hanadi F Sleiman, Donatien De Rochambeau
    US Patent 11,358,937
  9. Polynucleotide-poly (diol) conjugates, process of preparation and uses thereof
    Hanadi F Sleiman, Christopher J Serpell, Thomas GW Edwardson, Karina MM Carneiro
    US Patent Application 16/182,956
  10. Polynucleotide-poly (diol) conjugates, process of preparation and uses thereof
    Hanadi F Sleiman, Christopher J Serpell, Thomas GW Edwardson, Karina MM Carneiro
    US Patent Application 15/584,089
  11. Polynucleotide-poly (diol) conjugates, process of preparation and uses thereof
    Hanadi F Sleiman, Christopher J Serpell, Thomas GW Edwardson, Karina MM Carneiro
    US Patent Application 14/623,911
  12. Polymer compositions and uses thereof
    Hanadi Sleiman, Bingzhi Chen, Kim Metera
    US Patent 8,324,358
  13. Polymer compositions and uses thereof
    Hanadi Sleiman, Bingzhi Chen
    EP Patent Application 06,741,575 A
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