Our Group

DNA Structures for Cancer Therapy

Our research team creates structures from DNA and RNA as targeted medicines for the treatment of cancer. To do this, we study and control the fundamental self-assembly properties of DNA, polymers and supramolecular materials.

DNA Supramolecular Chemistry

Utilizing only a minimal set of DNA strands, we build unique 3D structures for uses in applications such as drug delivery and organization of other materials. This strategy allows us to make complex constructs using less DNA than other methods.

Expanding the DNA Toolbox

In the Sleiman lab, we work towards interfacing DNA with many other materials, including organic molecules, metal ions, and inorganic nanomaterials, to explore how DNA can be used to modify and organize these moieties. We also make sequence-defined polymers with DNA.

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